Russia: St. Petersburg - Singles - Main |
| 1/8-finals | Youzhny M. | Bautista-Agut R. | 1:2 (66:7, 6:3, 3:6) | details | 20.09.2018 |
| 1/16-finals | Basic M. | Youzhny M. | 0:2 (66:7, 4:6) | details | 19.09.2018 |
USA: US Open - Singles - Main |
| 1/64-finals | Baghdatis M. | Youzhny M. | 2:1 RET. (6:4, 6:4, 2:6, 3:1) | details | 28.08.2018 |
Canada: Toronto - Singles - Main |
| 1/16-finals | Youzhny M. | Haase R. | 0:2 (5:7, 2:6) | details | 08.08.2018 |
Canada: Toronto - Singles - Qualification |
| Final | Donskoy E. | Youzhny M. | WO. | details | 05.08.2018 |
| Semi-finals | Galarneau A. | Youzhny M. | 0:2 (3:6, 4:6) | details | 04.08.2018 |
USA: Washington - Singles - Main |
| 1/32-finals | Youzhny M. | Rubin N. | 0:2 (4:6, 4:6) | details | 31.07.2018 |
USA: Atlanta - Singles - Main |
| 1/8-finals | Youzhny M. | Zverev M. | 0:2 (4:6, 2:6) | details | 25.07.2018 |
| 1/16-finals | Youzhny M. | Reinberg E. | 2:0 (6:2, 6:0) | details | 25.07.2018 |
Kazakhstan: Astana - Singles - Main |
| 1/8-finals | Youzhny M. | Myneni S. | 1:2 (6:3, 4:6, 3:6) | details | 18.07.2018 |
| 1/16-finals | Youzhny M. | Gonzalez A. | 2:1 (6:3, 2:6, 7:5) | details | 17.07.2018 |
United Kingdom: Wimbledon - Singles - Main |
| 1/64-finals | Karlovic I. | Youzhny M. | 3:1 (4:6, 7:5, 7:67, 6:3) | details | 02.07.2018 |
Turkey: Antalya - Singles - Main |
| 1/16-finals | Youzhny M. | Haase R. | 1:2 (64:7, 7:65, 4:6) | details | 26.06.2018 |
Turkey: Antalya - Singles - Qualification |
| Final | Youzhny M. | Grigelis L. | 2:1 (65:7, 6:4, 6:2) | details | 24.06.2018 |
| Semi-finals | Youzhny M. | Dancevic F. | 2:0 (7:62, 6:1) | details | 23.06.2018 |
Germany: Halle - Singles - Main |
| 1/16-finals | Thiem D. | Youzhny M. | 2:0 (7:65, 6:2) | details | 18.06.2018 |
Germany: Halle - Singles - Qualification |
| Final | Berrettini M. | Youzhny M. | 0:2 (3:6, 67:7) | details | 17.06.2018 |
| Semi-finals | Bemelmans R. | Youzhny M. | 0:2 (64:7, 2:6) | details | 16.06.2018 |
Germany: Stuttgart - Singles - Main |
| 1/16-finals | Youzhny M. | Zverev M. | 0:2 (65:7, 3:6) | details | 11.06.2018 |
Germany: Stuttgart - Singles - Qualification |
| Final | Youzhny M. | Gerasimov E. | 2:0 (6:3, 6:2) | details | 10.06.2018 |
| Semi-finals | Youzhny M. | Guez D. | 2:0 (6:2, 6:3) | details | 09.06.2018 |
United Kingdom: Surbiton - Singles - Main |
| 1/16-finals | Youzhny M. | King K. | 0:2 (64:7, 5:7) | details | 04.06.2018 |
France: French Open - Singles - Main |
| 1/64-finals | Jaziri M. | Youzhny M. | 3:2 (2:6, 6:2, 6:2, 3:6, 6:2) | details | 28.05.2018 |
Italy: Rome - Singles - Qualification |
| Final | Jaziri M. | Youzhny M. | 2:1 (6:4, 3:6, 6:3) | details | 13.05.2018 |
| Semi-finals | Youzhny M. | Fritz T. | 2:1 (6:4, 3:6, 6:4) | details | 12.05.2018 |
Spain: Madrid - Singles - Qualification |
| Final | Delbonis F. | Youzhny M. | 2:0 (6:3, 6:1) | details | 06.05.2018 |
| Semi-finals | Berrettini M. | Youzhny M. | 1:2 (6:4, 3:6, 2:6) | details | 05.05.2018 |
Turkey: Istanbul - Singles - Main |
| 1/16-finals | Fabbiano T. | Youzhny M. | 2:0 (6:1, 6:1) | details | 01.05.2018 |
Hungary: Budapest - Singles - Main |
| 1/8-finals | Seppi A. | Youzhny M. | 2:0 (6:1, 6:2) | details | 26.04.2018 |
| 1/16-finals | Piros Z. | Youzhny M. | 0:2 (3:6, 3:6) | details | 25.04.2018 |
USA: Miami - Singles - Main |
| 1/16-finals | Isner J. | Youzhny M. | 2:0 (6:4, 6:3) | details | 25.03.2018 |
| 1/32-finals | Youzhny M. | Muller G. | 2:1 (4:6, 6:4, 6:2) | details | 23.03.2018 |
| 1/64-finals | Pella G. | Youzhny M. | 0:2 (63:7, 62:7) | details | 22.03.2018 |
USA: Irving - Singles - Main |
| 1/8-finals | De Minaur A. | Youzhny M. | 2:1 (6:2, 2:6, 6:2) | details | 15.03.2018 |
| 1/16-finals | Youzhny M. | Ebden M. | 2:1 (3:6, 6:1, 7:64) | details | 13.03.2018 |
USA: Indian Wells - Singles - Main |
| 1/64-finals | Youzhny M. | Sousa J. | 1:2 (6:4, 4:6, 64:7) | details | 09.03.2018 |
USA: Indian Wells - Singles - Main |
| 1/16-finals | Youzhny M. | Laaksonen H. | 0:1 RET. (63:7, 0:2) | details | 26.02.2018 |
USA: Delray Beach - Singles - Main |
| 1/8-finals | Youzhny M. | Fritz T. | 1:2 (1:6, 6:4, 3:6) | details | 22.02.2018 |
| 1/16-finals | Youzhny M. | Sela D. | 2:0 (7:5, 6:4) | details | 20.02.2018 |
USA: New York - Singles - Main |
| 1/8-finals | Youzhny M. | Querrey S. | 0:2 (4:6, 3:6) | details | 16.02.2018 |
| 1/16-finals | Youzhny M. | Ebden M. | 2:1 (3:6, 6:3, 6:4) | details | 14.02.2018 |
Bulgaria: Sofia - Singles - Main |
| 1/16-finals | Youzhny M. | Seppi A. | 0:2 (3:6, 4:6) | details | 07.02.2018 |
France: Quimper - Singles - Main |
| 1/16-finals | Trungelliti M. | Youzhny M. | CAN. | details | 30.01.2018 |
France: Rennes - Singles - Main |
| 1/8-finals | Youzhny M. | Sakharov G. | 0:2 (4:6, 1:6) | details | 24.01.2018 |
| 1/16-finals | Youzhny M. | Moutet C. | 2:0 (6:1, 6:2) | details | 23.01.2018 |