 USA: Indian Wells - Singles - Qualification |
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| 1/32-finals | Spadea V. | Alves T. | 1:2 (1:6, 7:6, 0:6) | details | 09.03.2010 |
| USA: Delray Beach - Singles - Main |
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| 1/16-finals | Spadea V. | Giraldo S. | 0:2 (2:6, 3:6) | details | 24.02.2010 |
| USA: Champaign - Singles - Main |
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| | Strode B. | Spadea V. | 2:0 (7:5, 6:2) | details | 16.11.2009 |
| USA: Knoxville - Singles - Main |
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| | Odesnik W. | Spadea V. | 2:0 (7:5, 7:6) | details | 11.11.2009 |
| USA: Charlottesville - Singles - Main |
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| | Spadea V. | Young D. | 1:2 (4:6, 7:5, 0:6) | details | 03.11.2009 |
| USA: Calabasas - Singles - Main |
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| | Spadea V. | Gregorc L. | 1:2 (3:6, 7:6, 4:6) | details | 20.10.2009 |
| USA: Tiburon - Singles - Main |
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| | Levine J. | Spadea V. | 2:1 (2:6, 6:2, 6:2) | details | 15.10.2009 |
| | Spadea V. | Matosevic M. | 2:1 (2:6, 7:6, 6:0) | details | 14.10.2009 |
| USA: Sacramento - Singles - Main |
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| | Spadea V. | Giraldo S. | 0:2 (1:6, 6:7) | details | 07.10.2009 |
| | Spadea V. | Kuznetsov Al. | 2:0 (6:3, 7:6) | details | 06.10.2009 |
| USA: Tulsa - Singles - Main |
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| | Spadea V. | Yani M. | 0:2 (2:6, 2:6) | details | 15.09.2009 |
| USA: US Open - Singles - Qualification |
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| Quarter-finals | Spadea V. | Gregorc L. | 0:2 (4:6, 6:7) | details | 26.08.2009 |
| USA: Los Angeles - Singles - Main |
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| 1/16-finals | Spadea V. | Kendrick R. | 0:2 (0:6, 0:6) | details | 28.07.2009 |
| USA: Indianapolis - Singles - Main |
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| 1/16-finals | Spadea V. | Sela D. | 0:2 (5:7, 1:6) | details | 21.07.2009 |
| USA: Newport - Singles - Main |
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| 1/16-finals | Spadea V. | Brands D. | 0:2 (0:6, 4:6) | details | 06.07.2009 |
| USA: Winnetka - Singles - Main |
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| 1/16-finals | Wolmarans F. | Spadea V. | 2:0 (7:63, 6:4) | details | 30.06.2009 |
 United Kingdom: Wimbledon - Singles - Main |
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| 1/32-finals | Spadea V. | Andreev I. | 0:3 (3:6, 5:7, 2:6) | details | 24.06.2009 |
| 1/64-finals | Capdeville P. | Spadea V. | 0:3 (0:6, 4:6, 5:7) | details | 22.06.2009 |
| USA: Yuba City - Singles - Main |
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| 1/16-finals | Spadea V. | Duclos P. | 1:2 (4:6, 6:2, 2:6) | details | 04.06.2009 |
| USA: Carson 2 - Singles - Main |
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| 1/16-finals | Spadea V. | Ryderstedt M. | 0:2 (4:6, 3:6) | details | 26.05.2009 |
| USA: Sarasota - Singles - Main |
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| 1/8-finals | Ward J. | Spadea V. | 1:0 RET. (6:0, 5:2) | details | 14.05.2009 |
| 1/16-finals | Berankis R. | Spadea V. | 1:2 (7:6, 4:6, 3:6) | details | 12.05.2009 |
| USA: Savannah - Singles - Main |
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| 1/16-finals | Russell M. | Spadea V. | 2:0 (6:2, 7:5) | details | 05.05.2009 |
| USA: Tallahassee - Singles - Main |
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| 1/8-finals | Spadea V. | Amritraj P. | 0:2 (4:6, 1:6) | details | 22.04.2009 |
| 1/16-finals | Spadea V. | Goodall J. | 2:1 (5:7, 7:5, 7:5) | details | 20.04.2009 |
| USA: Baton Rouge - Singles - Main |
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| 1/16-finals | Juska A. | Spadea V. | 2:1 (7:63, 4:6, 6:2) | details | 07.04.2009 |
| USA: Miami - Singles - Qualification |
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| | Mello R. | Spadea V. | 2:0 (7:6, 6:0) | details | 24.03.2009 |
| | Zeballos H. | Spadea V. | 0:2 (0:6, 3:6) | details | 23.03.2009 |
| USA: Indian Wells - Singles - Main |
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| 1/64-finals | Spadea V. | Kunitsyn I. | 0:2 (3:6, 4:6) | details | 12.03.2009 |
| USA: Delray Beach - Singles - Main |
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| 1/8-finals | Fish M. | Spadea V. | 2:0 (6:4, 6:1) | details | 26.02.2009 |
| 1/16-finals | Spadea V. | Gremelmayr D. | 2:1 (2:6, 7:5, 6:1) | details | 24.02.2009 |
| USA: Memphis - Singles - Main |
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| 1/16-finals | Spadea V. | Guccione C. | 0:2 (6:7, 6:7) | details | 16.02.2009 |
| USA: San Jose - Singles - Main |
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| 1/16-finals | Spadea V. | Blake J. | 0:2 (3:6, 4:6) | details | 12.02.2009 |
| USA: Carson - Singles - Main |
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| Semi-finals | Spadea V. | Odesnik W. | 0:2 (2:6, 3:6) | details | 31.01.2009 |
| Quarter-finals | Spadea V. | Young D. | 2:0 (6:3, 6:1) | details | 30.01.2009 |
| 1/8-finals | Spadea V. | Polansky P. | 2:0 (7:61, 6:2) | details | 29.01.2009 |
| 1/16-finals | Spadea V. | Widom T. | 2:1 (64:7, 7:5, 6:4) | details | 27.01.2009 |
 Australia: Australian Open - Main |
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| 1/64-finals | Spadea V. | Istomin D. | 0:3 (2:6, 5:7, 4:6) | details | 20.01.2009 |
| USA: Knoxville - Singles - Main |
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| 1/8-finals | Spadea V. | Russell M. | 0:2 (4:6, 3:6) | details | 19.11.2008 |
| 1/16-finals | Spadea V. | Devvarman S. | 1:0 RET. (7:67) | details | 19.11.2008 |
| USA: Champaign - Singles - Main |
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| 1/16-finals | Spadea V. | Ball C. | 1:2 (4:6, 6:3, 61:7) | details | 11.11.2008 |
| USA: US Open - Singles - Main |
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| 1/64-finals | Spadea V. | Safin M. | 2:3 (6:3, 2:6, 3:6, 6:4, 4:6) | details | 26.08.2008 |
| USA: New Haven - Singles - Main |
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| 1/32-finals | Darcis S. | Spadea V. | 1:0 RET. (7:5, 5:0) | details | 18.08.2008 |
| USA: Washington - Singles - Main |
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| 1/16-finals | Sela D. | Spadea V. | 2:0 (7:6, 6:3) | details | 11.08.2008 |
| USA: Los Angeles - Singles - Main |
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| 1/8-finals | Fish M. | Spadea V. | 2:1 (6:7, 6:1, 6:0) | details | 07.08.2008 |
| 1/16-finals | Spadea V. | Grosjean S. | 2:1 (6:3, 3:6, 6:3) | details | 05.08.2008 |
| USA: Indianapolis - Singles - Main |
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| 1/8-finals | Spadea V. | Querrey S. | 1:2 (6:4, 3:6, 4:6) | details | 18.07.2008 |