 USA: US Open - Doubles - Main |
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| 1/16-finals | Monroe N./Smith K. | Bolelli S./Fognini F. | 0:2 (64:7, 2:6) | details | 02.09.2022 |
| 1/32-finals | Monroe N./Smith K. | Fucsovics M./Molcan A. | 2:0 (7:66, 6:3) | details | 01.09.2022 |
| USA: US Open - Mixed Doubles - Main |
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| 1/16-finals | Pegula J./Krajicek A. | Montgomery R./Monroe N. | 2:0 (7:5, 6:4) | details | 31.08.2022 |
 Dominican Republic: Santo Domingo - Doubles - Main |
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| 1/8-finals | Dutra Da Silva D./Merino A. | King E./Monroe N. | 2:0 (6:4, 7:63) | details | 17.08.2022 |
| USA: Chicago - Doubles - Main |
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| 1/8-finals | Holt B./Monroe N. | Gille S./Smith J. P. | 0:2 (4:6, 5:7) | details | 11.08.2022 |
 Canada: Winnipeg - Doubles - Main |
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| 1/8-finals | Holt B./Monroe N. | Mejia N./Quiroz R. | 1:2 (62:7, 6:3, 11:13) | details | 28.07.2022 |
| USA: Indianapolis - Doubles - Main |
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| 1/8-finals | Raja P./Sharan D. | Hijikata R./Monroe N. | 2:0 (6:2, 7:5) | details | 20.07.2022 |
| USA: Newport - Doubles - Main |
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| 1/8-finals | Monroe N./Reboul F. | Albot R./Huey T. | 0:2 (3:6, 5:7) | details | 12.07.2022 |
 United Kingdom: Wimbledon - Doubles - Main |
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| 1/16-finals | Monroe N./Paul T. | Mektic N./Pavic M. | 1:3 (2:6, 6:3, 3:6, 2:6) | details | 02.07.2022 |
| 1/32-finals | Brkic T./Ramanathan R. | Monroe N./Paul T. | 0:3 (3:6, 65:7, 65:7) | details | 30.06.2022 |
| United Kingdom: Ilkley - Doubles - Main |
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| Quarter-finals | Cash J./Patten H. | Monroe N./Schnur M. | 2:0 (6:2, 6:1) | details | 16.06.2022 |
| 1/8-finals | Laaksonen H./Ritschard A. | Monroe N./Schnur M. | 1:2 (6:3, 5:7, 7:10) | details | 14.06.2022 |
| United Kingdom: Nottingham - Doubles - Main |
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| 1/8-finals | Cash J./Patten H. | Monroe N./Popyrin A. | 2:0 (6:3, 6:3) | details | 07.06.2022 |
| United Kingdom: Surbiton - Doubles - Main |
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| 1/8-finals | Monroe N./Skupski K. | Nakashima B./Popyrin A. | 0:2 (4:6, 67:7) | details | 02.06.2022 |
 France: French Open - Doubles - Main |
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| 1/16-finals | Ram R./Salisbury J. | Kecmanovic M./Monroe N. | 2:0 (6:3, 7:65) | details | 27.05.2022 |
| 1/32-finals | Kecmanovic M./Monroe N. | Basilashvili N./Sousa J. | 2:0 (6:4, 6:4) | details | 25.05.2022 |
 Tunisia: Tunis - Doubles - Main |
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| 1/8-finals | Geerts M./Vrbensky M. | Monroe N./Romboli F. | 2:0 (6:4, 6:3) | details | 17.05.2022 |
| France: Bordeaux - Doubles - Main |
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| Quarter-finals | Monroe N./Romboli F. | Hach Verdugo H./Oswald P. | 1:2 (6:4, 3:6, 4:10) | details | 12.05.2022 |
| 1/8-finals | Sharan D./Sitak A. | Monroe N./Romboli F. | 0:2 (4:6, 4:6) | details | 10.05.2022 |
 Czech Republic: Prague - Doubles - Main |
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| Semi-finals | Monroe N./Romboli F. | Paulson A./Pavlasek A. | 1:2 (7:5, 60:7, 8:10) | details | 06.05.2022 |
| Quarter-finals | De Jong J./Stevens B. | Monroe N./Romboli F. | 0:2 (4:6, 4:6) | details | 05.05.2022 |
| 1/8-finals | Balaji N. S./Nedunchezhiyan J. | Monroe N./Romboli F. | 0:2 (65:7, 2:6) | details | 04.05.2022 |
| Czech Republic: Ostrava - Doubles - Main |
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| 1/8-finals | Monroe N./Romboli F. | Furness E./Peniston R. | 0:2 (2:6, 4:6) | details | 27.04.2022 |
| USA: Houston - Doubles - Main |
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| Quarter-finals | Ebden M./Purcell M. | Monroe N./Romboli F. | 2:0 (6:2, 6:2) | details | 07.04.2022 |
| 1/8-finals | Monroe N./Romboli F. | Doumbia S./Reboul F. | 2:0 (6:3, 6:4) | details | 05.04.2022 |
| USA: Phoenix - Doubles - Main |
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| 1/8-finals | Monroe N./Smith J. P. | Huey T./Kudla D. | 0:2 (2:6, 4:6) | details | 15.03.2022 |
 Chile: Santiago - Doubles - Main |
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| 1/8-finals | Monroe N./Withrow J. | Delbonis F./Duran G. | 1:2 (3:6, 6:3, 7:10) | details | 22.02.2022 |
| USA: Delray Beach - Doubles - Main |
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| Quarter-finals | Monroe N./Withrow J. | Nedovyesov A./Qureshi A. | 0:2 (64:7, 5:7) | details | 18.02.2022 |
| 1/8-finals | Monroe N./Withrow J. | Vance J./Vance J. | 2:0 (6:3, 6:4) | details | 16.02.2022 |
| 1/8-finals | Monroe N./Withrow J. | Kokkinakis T./Thompson J. | CAN. | details | 16.02.2022 |
| USA: Dallas - Doubles - Main |
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| 1/8-finals | Hach Verdugo H./Reyes-Varela M. A. | Monroe N./Sandgren T. | CAN. | details | 09.02.2022 |
 India: Pune - Doubles - Main |
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| 1/8-finals | Cerretani J./Monroe N. | Bopanna R./Ramanathan R. | 1:2 (3:6, 6:3, 7:10) | details | 02.02.2022 |
 Australia: Australian Open - Doubles - Main |
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| 1/32-finals | Monroe N./Tiafoe F. | Puetz T./Venus M. | 0:2 (1:6, 63:7) | details | 19.01.2022 |
| Australia: Adelaide 2 - Doubles - Main |
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| 1/8-finals | Monroe N./Rune H. | Behar A./Escobar G. | 0:2 (2:6, 4:6) | details | 12.01.2022 |
| 1/16-finals | Monroe N./Rune H. | Kwon S./Sitak A. | 2:0 (6:3, 7:61) | details | 10.01.2022 |
| Australia: Adelaide - Doubles - Main |
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| 1/8-finals | Dodig I./Melo M. | Monroe N./Tiafoe F. | 2:1 (63:7, 7:5, 10:8) | details | 06.01.2022 |
| 1/16-finals | Reese H./Verbeek S. | Monroe N./Tiafoe F. | 0:2 (64:7, 2:6) | details | 03.01.2022 |
| USA: World TeamTennis - Doubles - Main |
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| | Giron M./Eubanks C. | Monroe N./Paul T. | 1:0 (5:42) | details | 27.11.2021 |
| | Paul T./Monroe N. | Johnson S./Krajicek A. | 0:1 (3:5, 7:6) | details | 26.11.2021 |
| | Kudla D./King D. | Paul T./Monroe N. | 0:1 (2:5) | details | 25.11.2021 |
| | Blumberg W./Vukic A. | Monroe N./Paul T. | 1:0 (5:2) | details | 24.11.2021 |
| | Giron M./Eubanks C. | Paul T./Monroe N. | 0:1 (1:5) | details | 22.11.2021 |
| USA: World TeamTennis - Mixed Doubles - Main |
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| | McNally C./Arevalo M. | Guarachi A./Monroe N. | 0:1 (3:5) | details | 20.11.2021 |