Argentina: Buenos Aires - Singles - Main |
| 1/16-finals | Del Potro J. | Delbonis F. | 0:2 (1:6, 3:6) | details | 09.02.2022 |
United Kingdom: London - Singles - Main |
| 1/8-finals | Del Potro J. | Lopez F. | WO. | details | 21.06.2019 |
| 1/16-finals | Del Potro J. | Shapovalov D. | 2:0 (7:5, 6:4) | details | 19.06.2019 |
France: French Open - Singles - Main |
| 1/8-finals | Khachanov K. | Del Potro J. | 3:1 (7:5, 6:3, 3:6, 6:3) | details | 03.06.2019 |
| 1/16-finals | Thompson J. | Del Potro J. | 0:3 (4:6, 4:6, 0:6) | details | 01.06.2019 |
| 1/32-finals | Nishioka Y. | Del Potro J. | 2:3 (7:5, 4:6, 2:6, 7:65, 2:6) | details | 30.05.2019 |
| 1/64-finals | Jarry N. | Del Potro J. | 1:3 (6:3, 2:6, 1:6, 4:6) | details | 28.05.2019 |
Italy: Rome - Singles - Main |
| Quarter-finals | Djokovic N. | Del Potro J. | 2:1 (4:6, 7:66, 6:4) | details | 17.05.2019 |
| 1/8-finals | Ruud C. | Del Potro J. | 0:2 (4:6, 4:6) | details | 16.05.2019 |
| 1/16-finals | Goffin D. | Del Potro J. | 0:2 (4:6, 2:6) | details | 16.05.2019 |
Spain: Madrid - Singles - Main |
| 1/16-finals | Djere L. | Del Potro J. | 2:1 (6:3, 2:6, 7:5) | details | 08.05.2019 |
USA: Delray Beach - Singles - Main |
| Quarter-finals | Del Potro J. | McDonald M. | 1:2 (4:6, 6:3, 65:7) | details | 23.02.2019 |
| 1/8-finals | Del Potro J. | Opelka R. | 2:0 (6:4, 6:4) | details | 22.02.2019 |
| 1/16-finals | Del Potro J. | Nishioka Y. | 2:0 (6:3, 7:5) | details | 20.02.2019 |
China: Shanghai - Singles - Main |
| 1/8-finals | Del Potro J. | Coric B. | 0:1 RET. (5:7) | details | 11.10.2018 |
| 1/16-finals | Del Potro J. | Gasquet R. | 2:0 (7:5, 7:67) | details | 10.10.2018 |
China: Beijing - Singles - Main |
| Final | Del Potro J. | Basilashvili N. | 0:2 (4:6, 4:6) | details | 07.10.2018 |
| Semi-finals | Del Potro J. | Fognini F. | WO. | details | 06.10.2018 |
| Quarter-finals | Del Potro J. | Krajinovic F. | 2:0 (6:3, 6:0) | details | 05.10.2018 |
| 1/8-finals | Del Potro J. | Khachanov K. | 2:0 (6:4, 7:64) | details | 03.10.2018 |
| 1/16-finals | Del Potro J. | Ramos A. | 2:0 (7:5, 6:2) | details | 02.10.2018 |
USA: US Open - Singles - Main |
| Final | Del Potro J. | Djokovic N. | 0:3 (3:6, 64:7, 3:6) | details | 09.09.2018 |
| Semi-finals | Nadal R. | Del Potro J. | 0:2 RET. (63:7, 2:6) | details | 07.09.2018 |
| Quarter-finals | Del Potro J. | Isner J. | 3:1 (65:7, 6:3, 7:64, 6:2) | details | 04.09.2018 |
| 1/8-finals | Del Potro J. | Coric B. | 3:0 (6:4, 6:3, 6:1) | details | 03.09.2018 |
| 1/16-finals | Del Potro J. | Verdasco F. | 3:0 (7:5, 7:66, 6:3) | details | 01.09.2018 |
USA: Cincinnati - Singles - Main |
| Quarter-finals | Goffin D. | Del Potro J. | 2:0 (7:65, 7:64) | details | 18.08.2018 |
| 1/8-finals | Kyrgios N. | Del Potro J. | 1:2 (64:7, 7:66, 2:6) | details | 17.08.2018 |
| 1/16-finals | Chung H. | Del Potro J. | 0:2 (2:6, 3:6) | details | 16.08.2018 |
Canada: Toronto - Singles - Main |
| 1/16-finals | Del Potro J. | Haase R. | CAN. | details | 08.08.2018 |
Mexico: Los Cabos - Singles - Main |
| Final | Del Potro J. | Fognini F. | 0:2 (4:6, 2:6) | details | 05.08.2018 |
| Semi-finals | Del Potro J. | Dzumhur D. | 2:0 (6:3, 7:66) | details | 04.08.2018 |
| Quarter-finals | Del Potro J. | Gerasimov E. | 2:0 (6:1, 6:1) | details | 03.08.2018 |
| 1/8-finals | Del Potro J. | Giron M. | 2:0 (7:5, 6:3) | details | 02.08.2018 |
United Kingdom: Wimbledon - Singles - Main |
| Quarter-finals | Del Potro J. | Nadal R. | 2:3 (5:7, 7:67, 6:4, 4:6, 4:6) | details | 11.07.2018 |
| 1/8-finals | Del Potro J. | Simon G. | 3:1 (7:61, 7:65, 5:7, 7:65) | details | 10.07.2018 |
| 1/16-finals | Del Potro J. | Paire B. | 3:0 (6:4, 7:64, 6:3) | details | 07.07.2018 |
| 1/32-finals | Del Potro J. | Lopez F. | 3:0 (6:4, 6:1, 6:2) | details | 05.07.2018 |
| 1/64-finals | Del Potro J. | Gojowczyk P. | 3:0 (6:3, 6:4, 6:3) | details | 03.07.2018 |
United Kingdom: Boodles Challenge - Singles - Main |
| | Del Potro J. | Fritz T. | 2:1 (6:4, 4:6, 15:13) | details | 27.06.2018 |
| | Zverev A. | Del Potro J. | CAN. | details | 27.06.2018 |