| Final | 1 | X | 2 | |
|---|
| Sf.Gheorghe - Sheriff Tiraspol | 0:1 | 17.43 | 7.10 | 1.11 | 21.05.2022 |
| Semi-finals | 1 | X | 2 | |
|---|
| Dinamo-Auto - Sheriff Tiraspol | 2:3 | | | | 26.04.2022 |
| Milsami - Sf.Gheorghe | 0:2 | 2.99 | 2.95 | 2.30 | 26.04.2022 |
| Quarter-finals | 1 | X | 2 | |
|---|
| Balti - Dinamo-Auto | 3:4 PEN. | 1.77 | 3.60 | 3.84 | 13.04.2022 |
| Zimbru Chisinau - Milsami | 0:3 | 3.34 | 3.34 | 1.98 | 13.04.2022 |
| Sf.Gheorghe - Floresti | 3:0 AWA. | | | | 12.04.2022 |
| Sheriff Tiraspol - Petrocub | 4:0 | 1.34 | 4.49 | 7.51 | 12.04.2022 |
| 1/8-finals | 1 | X | 2 | |
|---|
| Floresti - Singerei | 3:1 | | | | 27.10.2021 |
| Milsami - FCM Ungheni | 5:1 | | | | 27.10.2021 |
| Sheriff Tiraspol - Saksan | 6:0 | | | | 27.10.2021 |
| Drochia - Zimbru Chisinau | 1:4 | | | | 27.10.2021 |
|
| Balti - Cahul | WO. | | | | 26.10.2021 |
| Petrocub - Olimp Comrat | 6:0 | | | | 26.10.2021 |
| Sf.Gheorghe - Victoria | 1:0 | | | | 26.10.2021 |
| Sparta Selemet - Dinamo-Auto | 1:3 | | | | 26.10.2021 |
| 1/16-finals | 1 | X | 2 | |
|---|
| Cruiz Plus - FCM Ungheni | 1:4 | | | | 14.09.2021 |
| Inter Soroca - Victoria | 0:1 | | | | 14.09.2021 |
| Locomotiva Ocnita - Drochia | 0:4 | | | | 14.09.2021 |
| Maiak Chirsova - Cahul | 2:4 | | | | 14.09.2021 |
| Olimpia - Singerei | 1:3 | | | | 14.09.2021 |
| Real Succes - Olimp Comrat | 1:8 | | | | 14.09.2021 |
| Saksan - Speranis | 3:2 ET | | | | 14.09.2021 |
| Sparta Selemet - Dacia Buiucani | 2:0 ET | | | | 14.09.2021 |
|
| 1/32-finals | 1 | X | 2 | |
|---|
| Cimislia - Speranis | 0:1 | | | | 24.08.2021 |
| Codru Calarasi - FCM Ungheni | 2:3 | | | | 24.08.2021 |
| Cricova - Dacia Buiucani | 1:2 | | | | 24.08.2021 |
| Cruiz Plus - Iskra Ribnita | 1:0 | | | | 24.08.2021 |
| Congaz - Olimp Comrat | 0:6 | | | | 24.08.2021 |
| Locomotiva Ocnita - Edinet | 4:1 | | | | 24.08.2021 |
| Maiak Chirsova - Socol Copceac | 5:0 | | | | 24.08.2021 |
| Olimpia - Granicerul | 2:1 | | | | 24.08.2021 |
| Pepeni - Victoria | 1:6 | | | | 24.08.2021 |
| Riscani - Drochia | 0:5 | | | | 24.08.2021 |
| Saksan - Sucleia | 4:2 | | | | 24.08.2021 |
| Singerei - Falesti | 3:0 | | | | 24.08.2021 |
| Slobozia - Cahul | 2:3 | | | | 24.08.2021 |
| Stauceni - Real Succes | 1:3 | | | | 24.08.2021 |
| Vasieni - Sparta Selemet | 0:3 | | | | 24.08.2021 |
| Visoca - Inter Soroca | 0:3 AWA. | | | | 24.08.2021 |
